May 1, 2020

Aluminum phosphide (ALP) is a cheap, easily available agricultural pesticide which causes lethal poisoning by liberation of phosphine and. Aluminium Phosphide Poisoning: Management and Prevention of AlP poisoning, mediated by phosphine and mechanism of action have not been established. Aluminium phosphide (AlP) is a cheap solid fumigant and a highly toxic pesticide that is commonly used for grain preservation. AlP has currently generated.

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Indian J Med Sci. I wish for a great success for JCDR. Acute phosphine poisoning abroad on a grain freighter. This e-journal is fulfilling the commitments and objectives sincerely, as stated by Editor-in-chief in his preface to first edition i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care.

Ann Intern Med ; It is inflammable and may spontaneously ignite in air at ambient temperature at concentrations above the threshold limit range of 1. National Center for Biotechnology InformationU. Spontaneous Ignition Limits of Silane and Phosphine.

Table 2 Clinical presentation of the patients in ICU.

Related articles Aluminium phosphide management phosphine poisoning shock. Possible role of supportive measures in the absence of specific antidote. To evaluate the effectiveness of new treatment regimen and interventions to reduce the pousoning from celphos poisoning. Strengths of the journal: Acute aluminium phosphide poisoning AAlPP is a large, though under-reported, problem throughout the world, particularly in the Indian subcontinent. Strict implementation of nationwide pesticide regulation, including restricting the availability of poison, being aware of its toxicity and providing improved ceelphos management in consultation with regional or national poison control centers could further reduce the mortality due to AlP toxicity as there is no antidote available presently.


Karanth S, Nayyar V.

Management of celphos poisoning with a novel intervention: A ray of hope in the darkest of clouds

In addition to the corrosive action of phosphine, the mechanism of toxicity includes failure of cellular respiration due to the effect on mitochondria, inhibition of cytochrome C oxidase and formation of highly reactive hydroxyl radicals.

Late manifestation include liver and kidney toxicities. Unintentional poisoning by phosphine released from aluminum phosphide. Human toxicity occurs poosoning due to the ingestion of AlP commonest mode after exposure and injury from phosphine inhalation uncommon or even after absorption through the poisonin rare.

Aluminium and zinc phosphide poisoning. Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal poisoniny an outlet for their work.

The patient was irritable but was oriented. Since the first available report of AlP poisoning in the early s from India, it is now one of the most common causes of poisoning among agricultural pesticides.

Yatendra Singh Room no. Tissue magnesium content and histopathological changes in non-survivors of aluminium phosphide poisoning. Successful lipid resuscitation in multi-drug overdose with predominant tricyclic antidepressant toxidrome. Published by Wolters Kluwer – Medknow. The journal is indexed in many databases, though not in PubMed. Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, poisnoing reading, language check, computer operators, etc.

Pesticide poisoning, whether due to self, accidental, occupational or for homicidal purpose, is a global public health problem, and self-poisoning accounts for one-third of the world’s suicide rate.


An echocardiographic study in aluminium phosphide poisoning abstract J Assoc Physicians India. Goel A, Aggarwal P.

A year autopsy experience from a tertiary care hospital in northern India”. Aluminum phosphide ingestion – a clinico-pathologic study. In most of the studies, poor prognostic factors were presence of acidosis and shock. Discussion This patient presented with the usual initial symptoms after ingestion of ALP i. Online submission, publication and peer reviewing makes it a user-friendly journal.

Acute respiratory distress syndrome ARDS and exudative pleural effusions can develop. Although few lives have been saved here and there, doubt still remains about the nature of poison consumed, the amount of poison consumed, the time interval between consumption and resuscitation and so on.

An yearly reward for the best article authored can also incentivize the authors. Suicide by intentional ingestion of pesticides: Death due to acute hepatocellular toxicity and fulminant hepatic failure has also been reported in acute poisoning.

Management of celphos poisoning with a novel intervention: A ray of hope in the darkest of clouds

Br Med J ; In Aluminium phosphide poisoning garlic like odour is present at mouth and nostrils. The reversibility of myocardial injury over few days was objectively assessed by repeated echocardiography. Deparment of Health Education and Welfare, At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers.