Request PDF on ResearchGate | Radioanatomie des cancers du rhinopharynx | Rhinopharyngeal cancer is one of the best indications for conformal. Request PDF on ResearchGate | Cancers du cavum de l’adulte | The main objective of this work was to propose Radiothérapie des cancers du nasopharynx. Image en médecine. Les cancers du nasopharynx, dominés par les carcinomes épidermoïdes surtout de type undifferenciated carcinoma of.
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NPC occurs in children and adults. NPC differs significantly from other cancers of the head and neck in its occurrencecauses, clinical behavior, and treatment.
It is vastly more common in certain regions of East Asia and Africa than elsewhere, with viraldietary and genetic factors implicated in its causation. It is most common in males. It is a squamous cell carcinoma or an undifferentiated type. Squamous epithelial cells are a flat type of cell found in the skin and the membranes that line some body cavities. Differentiation means how different the cancer cells are from normal cells. Undifferentiated cells are cells that do not have their mature features or functions.
Swelling of the lymph nodes in the neck is the initial presentation in many people, and the diagnosis of NPC is often made by lymph node biopsy. Signs and symptoms related to the primary tumor include trismuspain, otitis medianasal regurgitation due to paresis loss of or impaired movement of the soft palatehearing loss and cranial nerve palsy paralysis. Larger growths may produce nasal obstruction or bleeding and a “nasal twang”. Metastatic spread may result in bone pain or organ dysfunction.
Rarely, a paraneoplastic syndrome of osteoarthropathy diseases of joints and bones may occur with widespread disease. Nasopharyngeal carcinoma NPC is caused by a combination of factors: The World Health Organization does not have set preventative measures for this virus because it is so easily spread and is worldwide.
Very rarely does Epstein-Barr virus lead to cancer, which suggests a variety of influencing factors. Other likely causes include genetic susceptibility, consumption of food in particular salted fish  containing carcinogenic volatile nitrosamines.
The cause of NPC particularly the endemic form seems to follow a multi-step process, in which EBV, ethnic background, and environmental carcinogens all seem to play an important role. More importantly, EBV DNA levels appear to correlate with treatment response and may predict disease recurrence, suggesting that they may be an independent indicator of prognosis. The mechanism by which EBV alters nasopharyngeal cells is being elucidated  to provide a rational therapeutic target.
The World Health Organization classifies nasopharyngeal carcinoma in three types. Type 1 I is keratinizing squamous cell carcinoma. Type 2a II is non-keratinizing squamous cell carcinoma. Type 2b III is undifferentiated carcinoma. Staging of nasopharyngeal carcinoma is based on clinical and radiologic examination.
Stage II is a tumor extending in the local area, or that with any evidence of limited rhinopyarynx nodal disease. Stage III is a large tumor with or without neck disease, or a tumor with bilateral neck disease. Ccancer carcinoma can be treated by surgery, by chemotherapyor by radiotherapy. The expression of EBV latent proteins within undifferentiated nasopharyngeal carcinoma can be potentially exploited for immune-based therapies. Nasopharynx cancer as of resulted in 65, deaths globally up from 45, in NPC is uncommon in the United States and most other nations, representing less than vu case perin most populations.
The cause of increased risk for NPC in these endemic regions is not clear. From Wikipedia, the free encyclopedia. Retrieved 2 October Seminars in Cancer Biology. Report of a case-control study in Hong Kong”. The Journal of Pathology.
Orphanet Journal of Rare Diseases. Applications of emerging immunotherapeutic strategies for Epstein—Barr virus-associated malignancies”. Nature Clinical Practice Oncology. A systematic rninopharynx for the Global Burden of Disease Study “. Journal of Translational Medicine. Chinese Journal of Cancer. Nasal cavity Esthesioneuroblastoma Nasopharynx Nasopharyngeal carcinoma Nasopharyngeal angiofibroma Larynx Laryngeal cancer Laryngeal papillomatosis. Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma.
Sarcoma Lymphoma Immature teratoma Melanoma. Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma. Mesothelioma Malignant solitary fibrous tumor.
Acinic cell cancwr Mucoepidermoid carcinoma Adenoid cystic carcinoma Salivary duct carcinoma Epithelial-myoepithelial carcinoma Polymorphous low-grade adenocarcinoma Hyalinizing clear cell carcinoma.
Prise en charge des cancers du cavum (rhinopharynx) – EM|consulte
Pleomorphic adenoma Warthin’s tumor. Infectious diseases — viral systemic diseases A80—B34 dhinopharynx, — MuV Mumps Cytomegalovirus Cytomegalovirus esophagitis. BK virus MuV Mumps. Retrieved from ” https: Head canncer neck cancer of respiratory tract Epstein—Barr virus-associated diseases Infectious causes of cancer Pharynx. All articles with dead external links Articles with dead external links from October Wikipedia articles needing page number citations from October Infobox medical condition new.
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Salivary gland malignant epithelial tumors Acinic cell carcinoma Mucoepidermoid carcinoma Adenoid cystic carcinoma Salivary duct carcinoma Epithelial-myoepithelial carcinoma Polymorphous low-grade adenocarcinoma Hyalinizing clear cell carcinoma.